{"id":19545,"date":"2017-06-08T11:00:05","date_gmt":"2017-06-08T15:00:05","guid":{"rendered":"http:\/\/pmedicine.org\/epatients\/?p=19545"},"modified":"2017-06-08T11:05:20","modified_gmt":"2017-06-08T15:05:20","slug":"eric-topol-landmark-digital-medicine-trial-patient-generated-data-improve-cancer-survival","status":"publish","type":"post","link":"https:\/\/participatorymedicine.org\/epatients\/2017\/06\/eric-topol-landmark-digital-medicine-trial-patient-generated-data-improve-cancer-survival.html","title":{"rendered":"Eric Topol: Landmark Digital Medicine Trial: Patient-Generated Data Improve Cancer Survival"},"content":{"rendered":"

Eric Topol published a Commentary<\/a> on Medscape describing a study published in JAMA in which cancer patients that tracked 12 symptoms and shared the tracking results with their health teams had a five months\u00a0increase in survival equivalent with some of the most promising\u00a0drugs.<\/p>\n

http:\/\/www.medscape.com\/viewarticle\/881243<\/a><\/p>\n

The conclusion of the commentary:<\/p>\n

Why is this trial so important? First, it is not a stand-alone result but the replication of one with concordant results, now with a fivefold increase in sample size and long-term follow-up (instead of premature discontinuation).<\/p>\n

Second, the improvement in survival of > 5 months compares quite favorably with the median survival improvement in major oncology drug trials, such as those seen with the exciting results of immunotherapy. Many of these trials have shown a 3-month median survival improvement for new drugs, leading to commercial approval and costing at least $100,000 per treatment.<\/p>\n

But unlike the drug trials, there was little promotion or coverage. The only major newspaper that reported on the trial was the Washington Post<\/em>.[4<\/a>]<\/sup> This might have been anticipated; there is no sponsor. The ASCO meeting is characterized by the reporting of hundreds of drug trials, but it turned out that a digital medicine trial had striking results that largely outperformed most of the expensive and heavily promoted biopharma interventions. The digital tracking strategy costs very little: an app, an algorithm, and a strategy for clinician response. But that represents a de minimis amount considering the outcome of improved survival\u2014or the new drug cost of $100,000 per patient.<\/p>\n

Most important, this trial emphasizes the role of engaging patients in tracking their symptoms and of generating their own data. Patients have long been neglected for having a more active role in their care, when in fact, given the appropriate tools, they represent true “blockbuster” potential for improving their outcomes.[5<\/a>]<\/sup><\/p><\/blockquote>\n

HT to our member Marilyn Mann for sharing the link in our Member’s Facebook Group. If you would like to join, you can do so here <\/a>(http:\/\/participatorymedicine.org\/join-us\/<\/a>)<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Eric Topol published a Commentary on Medscape describing a study published in JAMA in which cancer patients that tracked 12 symptoms and shared the tracking results with their health teams had a five months\u00a0increase in survival equivalent with some of the most promising\u00a0drugs. http:\/\/www.medscape.com\/viewarticle\/881243 The conclusion of the commentary: Why is this trial so important? […]<\/p>\n","protected":false},"author":14,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[12,87,5,4986,7],"tags":[5206,9,8044,6249,6307,8045],"coauthors":[],"class_list":["post-19545","post","type-post","status-publish","format-standard","hentry","category-found-on-the-net","category-net-friendly-docs","category-ptdoc-co-care","category-pm-tech","category-positive-patterns","tag-asco","tag-cancer","tag-digital-health","tag-eric-topol","tag-medscape","tag-tracking-symptoms"],"jetpack_publicize_connections":[],"yoast_head":"\nEric Topol: Landmark Digital Medicine Trial: Patient-Generated Data Improve Cancer Survival - SPM Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/participatorymedicine.org\/epatients\/2017\/06\/eric-topol-landmark-digital-medicine-trial-patient-generated-data-improve-cancer-survival.html\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Eric Topol: Landmark Digital Medicine Trial: Patient-Generated Data Improve Cancer Survival - SPM Blog\" \/>\n<meta property=\"og:description\" content=\"Eric Topol published a Commentary on Medscape describing a study published in JAMA in which cancer patients that tracked 12 symptoms and shared the tracking results with their health teams had a five months\u00a0increase in survival equivalent with some of the most promising\u00a0drugs. http:\/\/www.medscape.com\/viewarticle\/881243 The conclusion of the commentary: Why is this trial so important? 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