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Editors’ Note: This research article is the second of two companion papers on the topic of mindfulness to be published in this Journal. The first paper is a review article titled “Mindfulness in Participatory Medicine: Context and Relevance.”


Background and Objective: Proactive patient self-care is central to the model of Participatory Medicine. Mindfulness-based interventions are proving to be effective self-care learning modalities in a variety of medical and therapeutic settings. This naturalistic study offers a clinical account for the value of mindfulness by measuring enduring, positive, therapeutic outcomes, and a transformation of self-care.
Methods: The study followed one clinic’s empirical approach to assessing the outcome attributable to Mindfulness-Based Stress Reduction (MBSR) [1] participants who came with a wide diversity of health care concerns.
Findings: Significant and enduring improvements in participants’ perceived stress, self-care attitudes and behaviors, as well as physical, mental and social health status along with a long-term engagement in mindfulness practice were found. A survey of participants’ health care providers indicated that they perceived a positive transformation of self-care in their patients.
Implications: Along with a growing body of studies documenting the effectiveness of mindfulness-based learning interventions, this evidence demonstrates the ecological validity of mindfulness practice in the domain of participatory health care.
Keywords: Mindfulness, Mindfulness-Based Stress Reduction, MBSR, self-care, self-regulation, participatory medicine, meditation.
Citation: Rogers B, Christopher M, Sunbay-Bilgen Z. Mindfulness, self-care, and participatory medicine: a community’s clinical evidence. J Participat Med. 2013 Feb 20; 5:e9.
Published: February 20, 2013.
Competing Interests: The authors have declared that no competing interests exist.


Tom Ferguson recognized that the evolving model of healthcare called Participatory Medicine acknowledges patients, caregivers and their networks all as powerful medical resources.[2] He coined the term “e-patients” as those who actively collaborate to care for others, work with clinicians, shape research, and most relevant to this study, are active participants in their own self-care. While the emphasis in this evolving model of medicine has often been toward accessible information and computer networking, he recognized that medical information and technology alone might not be helpful. Rather, collaborating and communicating in order to enhance the power of self-care is far more effective. This model recognizes that empowering patients requires a transformation of the patient’s level of engagement, the relationship with their caregivers, and with their illness.

Acknowledging the power of this transformation, Jon Kabat-Zinn was one of the first to articulate the nature of participatory medicine in the medical literature.[3] He explained that the capacity to engage one’s illness and relationships is measurably enhanced via learning the practice of mindfulness meditation. More than 3 decades of research document the broad effectiveness of this approach.[4][5]

These are two complementary views. One mainly approaches via information, technology, and networked communities and the other via contemplative practice. What they have in common is their capacity to enhance these “inner resources for learning, growing, healing and personal transformation.[3]” The e-patient’s strengthened relationships with a network of caregivers and relevant information empower these inner resources. Likewise, via mindfulness practice, the patient’s transformed relationship with the internal experience of his or her own life, the enriched relationships with others, and a greater understanding of the context of their illness empowers them toward greater confidence to learn, grow, and heal.

Healing has many dimensions, and a host of these are touched by mindfulness practice. In a separately published article in this journal, Rogers and colleagues[5] review the arc of research on mindfulness practice, its consequences and employment in the domain of medicine and psychotherapy. A host of studies document how mindfulness alters the stress response and a number of physiological markers including immune response, inflammation, and blood pressure. Recent neurobiological studies have shown that learning mindfulness produces significant changes in brain structure and function associated with self-regulation, learning, memory, emotional regulation, perspective, and self-referential processing. Similarly, numerous studies have documented the impact of mindfulness practice on reducing the suffering associated with a growing number of medical and psychiatric disorders and life challenges: chronic pain, cancer, grieving, insomnia, irritable bowel syndrome, depression, and more. It follows that mindfulness has become an integral component of an evolving array of effective interventions.

In the MBSR groups in this study we used the definition offered by Kabat-Zinn: “Mindfulness means paying attention in a particular way: on purpose, in the present moment, and nonjudgmentally.[6]” The practice of mindfulness meditation concerns enhancing awareness of life’s experiences: physical sensations, thoughts, sounds, affective states, and more. As a consequence there is a tendency to be less reactive and the physiological, neurological, emotional, and social burdens of this reactivity begin to lift. Essentially, there is less suffering.

Central to an effective model of participatory health care, is first-person proactive self-care, what Bandura[7] terms the primacy of self-regulation in health care. Mindfulness is participatory and is a form of self-care requiring individual intention and proactive personal engagement. Studies measuring the impact of mindfulness practice on self-care have tended to document mental and physical health status measures along with various tests indexing levels of trait mindfulness or desirable mental states. These often go on to infer self-care as a consequence of improvements in such measures.[8][9][10][11][12] Moreover, most of these studies involve participant populations of clinicians or college students. To broaden the scope of understanding about the impact of mindfulness practice on self-care we developed and used a self-reported direct measure of self-care.[13] Likewise, the naturalistic design of this study broadens this understanding by following participants who learned mindfulness in a community-based clinical setting where most of the participants were referred by clinicians, family, and friends during the normal course of health care.

We investigated long-term changes in attitudes and behaviors toward self-care, health status, and continuity of mindfulness practice among MBSR participants in one community clinic (Study 1) and surveyed the health care professionals who cared for them in order to determine what changes clinicians see in their patients’ capacity for self-care as a consequence of mindfulness practice (Study 2). We hypothesized that there would be changes that reflected better health and more personal engagement. Our goal was to demonstrate that mindfulness practice supports the model of Participatory Medicine in two ways: (1) with enduring transformations toward positive medical and therapeutic outcomes via a personal learning intervention, and (2) demonstrating a long-term personal transformation that enhances proactive self-care.

Study 1: MBSR, Health Status, and Self-Care


Participants were recruited from 8-week MBSR courses offered through a stress reduction clinic in a healthcare-oriented yoga studio located in a medium-sized city in Oregon from Fall 2007 through Winter 2011 (14 total courses). All students who were enrolled in the MBSR courses over the four-year period were invited to complete pre- and post-program self-report measures. A total of 229 participants entered the course; 75% were women and the mean age was 47 (range 16-73, SD = 11.6). Income levels of participants varied from those on public assistance, to retired persons with fixed income, and the working middle class. Of the 218 participants who completed the program, 185 completed measures at pre- and post-MBSR and data from these participants were included for analysis. Additionally, we sent a followup questionnaire to all 185 participants in Fall 2011.We received completed data from 94 participants (51%).

MBSR Intervention.
MBSR is a learning intervention requiring proactive personal engagement. It is a particular way of learning mindfulness meditation that emerged in a hospital system over 30 years ago and was fashioned as a complement to medical care and therapy.[1] During this study we used that well-established program’s evaluation instruments and methods. [14] Participants completed an application process and interview prior to admission to the program. They committed to 24 hours of classroom instruction and over 30 hours of homework, 45 minutes per day. Each group met for eight 2.5-hour weekly sessions and for one 6.5-hour retreat on the 6th week of the program.

Activities and mindfulness-based skills learned in the program are primarily experiential. Three principal practices are introduced during the program and constitute most of the homework and classroom time for participants. The body-scan meditation involves step-wise guided attention to sensations across all regions of the body from toes to head. Sitting meditation is introduced as a practice of attention to the experience of breathing with a quality of openness to the various experiences of life, including sensation, thought, emotion, and sound. Mindful yoga is introduced as a gentle, adapted form of mindful movement designed to offer an appropriate level of physical movement emphasizing direct experience. Other principal elements introduced during the program include walking meditation, eating meditation, informal mindfulness of daily actives, and guided meditations such as loving-kindness. Didactic learning includes group interaction, dialogue and inquiry about the experiential practices as well as about the subject of stress management. Participants were asked to complete evaluations and testing using the measures described below. The first author (B.R.) was the primary instructor for all 14 courses; he is an MBSR instructor certified by the Center for Mindfulness at the University of Massachusetts Medical School.

Perceived Stress Scale (PSS-10). The 10-item PSS-10 [15] was used to assess the degree to which situations in life are perceived as stressful. Items on the PSS-10 are designed to assess how unpredictable, uncontrollable, and overloaded participants find their lives. Items are rated on a 5-point Likert-type scale ranging from 0 = never to 4 = very often. Four items that are worded in a positive direction are reverse-scored and responses to the 10 items are summed to create a psychological stress score, with higher scores indicating greater psychological stress. The PSS-10 has adequate internal consistency (α = .78) and has demonstrated expected correlations with a variety of constructs.[15]

Duke Health Profile (DUKE). The DUKE[16] is a 17-item, multi-dimensional questionnaire designed to measure self-reported functional health status among primary care populations. This brief, accessible measure was developed to assess multifaceted dimensions of health and well-being in a family medicine setting, which made it ideally suited for the naturalistic design used in this study. We used six DUKE subscales to measure function: physical, mental, social health, general health, perceived health and self-esteem. Three subscales were used to measure dysfunction: anxiety, depression, and pain. Six items that are worded in a positive direction are reverse-scored and the responses to different constellations of items are summed to create the various subscale scores. All items are rated on a 3-point Likert-type scale. The DUKE subscales have demonstrated evidence of criterion, convergent, and discriminant validity, as well as acceptable reliability for the overall scale. [17][18]

MBSR Followup Questionnaire (FQ). The FQ [14][19] is a two-part retrospective self-report questionnaire that has been used for many years to follow results of MBSR courses at the University of Massachusetts Medical School’s Center for Mindfulness and has also been reported on in published MBSR research.[20][21][22]The eight items in part 1, referred to in literature as the Summary Outcome Questionnaire[23], were used to assess pain frequency, pain severity, medication use, activity levels, energy levels, feelings in general, ability to cope with stress, and blood pressure. When responding to these items participants are instructed to “compare how you are now compared to how you were before taking the MBSR Program”. These items are rated on a 6-point Likert-type scale ranging from 1 = much worse to 6 = greatly improved (unless the participant, by choosing 0, indicated that aspect of health was not a problem to begin with).

Part 2 includes 10 items used to measure “how much change, if any, has occurred for you in the following attitudes and behaviors as a direct result of your participation in the MBSR Program.” We selected the 5 items from the part 2 scale we believed best assessed self-care and used them in this study, and a factor analysis of all 10 items [13] supported these 5 items loading onto a “mindful self-care” index (MSCI). These items are “knowing I need to take better care of myself,” “actually taking better care of myself,” “believing I can improve my health,” “feeling assertive and able to express my needs,” and “correcting negative health habits and behaviors.” To further tap the participatory medicine aspect of self-care we added an additional item to the MSCI at long-term followup, “feeling I am able to communicate my needs effectively to my healthcare provider(s).” These items are rated on a 4-point Likert-type scale ranging from 1 = negative change to 4 = positive change. In the current sample, Cronbach’s alpha for the 8 items in part 1 is .69 and for the 6 items in part 2 is .83.

Meditation Practice Questionnaire (MPQ). We included four items in this study to measure how much participants continued the practices they learned in the MBSR program. We asked participants: (1) how often they do formal MBSR practices (eg, sitting meditation, yoga, body scan), (2) average duration of each formal MBSR practice, (3) how often they do informal MBSR practices (ie, mindfulness of daily activities like eating, walking, speaking, listening, journaling, etc) and (4) when engaged in daily activities (eg, eating, walking, speaking, listening, journaling, etc) what percent of the time they do them mindfully. All four items were rated on a 7-point Likert-type scale, and the two formal meditation items and the two informal meditation items were summed to form a formal and informal meditation index, respectively. These measures avoid many of the weaknesses of mindfulness measurement articulated by Grossman[24] by directly assessing participants’ practice of mindfulness skills they learned through their participation in the MBSR program.

Participants completed either the PSS-10 or the DUKE pre- and post-MBSR course on the first day of class, last day of class, and at followup in Fall 2011. The PSS-10 was completed pre- and post-MBSR by 118 participants over eight courses from Fall 2007 through Summer 2009. The DUKE was completed pre- and post-MBSR by 66 participants over six courses from Fall 2009 to Spring 2011. The FQ was completed Post-MBSR by all 185 participants over the 14 MBSR programs from Fall 2007 through Winter 2011. The PSS-10 or DUKE (depending upon which one they completed at pre- and post-MBSR), SC, and MPQ were completed by 93 participants in the followup survey in Fall 2011. For participants who were administered the PSS-10 at followup (n = 55), the mean duration from post-MBSR to followup was 3 years and for participants administered the DUKE at followup (n = 38) the mean duration from post-MBSR to followup was 1.5 years.

Design and Analyses

To assess pre- and post-MBSR health status change experienced by participants for each outcome, paired t-tests were used and a Bonferroni adjustment was made to control family-wise error rate (ie, to minimize the likelihood of Type I error with the significance value set at p < 0.005 for each t-test – 10 in total). To determine the magnitude of change, effect sizes (ES) were calculated using Cohen’s d. The general magnitude of the change was assessed using percentage change from pre- to post-MBSR levels. Repeated measures one-way analyses of variance (ANOVAs) were used to investigate change in outcome variables over three data points (pre-, post-MBSR, and followup). ANOVAs were selected over a combined MANOVA for the dependent variables to conserve power and because homogeneity of variance assumptions were met for all tests, and the significance value set at p < 0.005 for each ANOVA. Partial eta squared was used to evaluate the ES for the ANOVA’s. Contrast tests were used to further identify differences in functioning at each time interval (ie, pre-, post-MBSR, and followup) for all outcome measures, and the significance value was set at p < 0.0025 for each contrast test (20 in total – 2 per ANOVA). Pearson’s correlations were calculated to assess the relationship between self-care, mindfulness practice, and stress.


Table 1 presents results for the eight items on Part 1 of the FQ. The vast majority of participants endorsed difficulty coping with stress and feeling poorly upon entering the MBSR course, and nearly all of them (> 95%) indicated that they felt better and were coping better after the 8-week MBSR course. Similarly, most participants came with problems of low physical activity, energy and stamina. The majority of these people (> 60%) reported improvements as well. Seventy-five percent of participants entered the program taking medication, and nearly one-third (31%) reported decreased usage as a result of their participation. Over 50% of participants reported that pain was a problem prior to beginning MBSR, and 59% of these participants reported less frequency and severity of pain. Nearly 35% of participants reported having high blood pressure, and 49% reported that it decreased.

Table 1. Percentage of Participants Reporting Health Status Improvements on Part 1 of the Followup Questionnaire Post-MBSR Training.

Results for the mindful self-care index (MSCI) are shown in Table 2. A large majority of participants reported positive changes in self-care attitudes and behaviors as a result of the MBSR program. The pre- and post-MBSR results for the PSS-10 and DUKE subscales are presented in Table 3. On the PSS-10 and a majority of DUKE subscales, participants evidenced statistically significant changes (p < .0008 for 8 of 10 measures, and p = .02 and .05 for the other two) toward improved health. Most Cohen’s d values were indicative of medium to large effects across domains. More specifically, participants experienced the largest changes and most robust effects for perceived stress (d = 1.29), general health (d =.80), mental health (d =.78), depression (d = .76), and anxiety (d = .68). Table 2. Percentage of Participants Reporting Positive Changes in Self-Care Attitudes and Behavior at Both Post-MBSR and Long-Term Followup.

Table 3. Changes in Stress and Health from Pre- to Post-MBSR.

Fifty-one percent (94 out of 185) of program participants who completed the pre- and post-MBSR program testing responded to the followup survey. There were no statistically significant differences between followup respondents and non-respondents on any demographic variables and PSS-10 or DUKE scores at post-MBSR. Table 4 presents outcome over all three periods: pre-, post-MBSR, and followup for those that completed all three (n = 93). Similar to the pre- and post-MBSR results, participants endorsed significant improvement on all outcome measures with the exception of pain (p = .122) and perceived health (p = .185). ANOVA results for the three time points (i.e., pre-, post-MBSR, and followup) revealed that most of the statistically significant changes that occurred at post-MBSR course were maintained at the followup. More specifically, statistically non-significant contrast tests comparing post-MBSR to followup scores indicated that participants maintained improvements made during the course on all measures. For example there were no statistically significant differences between post-MBSR and followup scores: PSS-10 (t = 2.01; p = .06), physical health (t = 1.73; p = .10), mental health (t = .59; p = .62), social health (t = .33; p = .76), general health (t = .42; p = .69), perceived health (t = 1.21; p = .23), self-esteem (t = .26; p = .83), anxiety (t = .20; p = .84), depression (t = .46; p = .65); and pain (t = 1.13; p = .33).

Table 4. Scores on Stress and Health at Pre-, Post-, and Long-Term Followup After MBSR.

Frequency of formal and informal meditation practice at followup is presented in Table 5. The majority of participants endorsed ongoing mindfulness practice, with only 14% never practicing formally and only 6% never practicing informally. In addition, participants endorsed an average range of duration for each formal meditation practice of 21-30 minutes and when engaging in daily activities, doing them mindfully on average 31-40% of the time. As shown in Table 6, there were a number of statistically significant correlations among variables at followup. More specifically, informal meditation practices and self-care were significantly negatively correlated with stress, whereas formal meditation practice was uncorrelated with stress. Additionally, self-care was significantly positively correlated with informal and formal meditation practice, and significantly negatively correlated with stress.

Table 5. Continuity of Mindfulness Practice at Long-Term Followup After MBSR.

Table 6. Pearson Correlations Between Stress, Self-Care, and Mindfulness Practice at Long-Term Followup.


The results in this study reflect the global nature of the consequences of learning and practicing mindfulness meditation. Simultaneous long-term improvements in measures of physical, mental, personal, and social health underscore the ability of this practice to reduce suffering in a broad sense.[1][25][26] Our results confirm previous findings in other studies of enduring positive outcomes (eg, [20][21][27][28][29][30]). Likewise, the number of recent, well designed quasi-experimental and controlled studies supports our finding of internal validity of MBSR in clinical settings.[31][32][33][34][35][36][37]

Unlike other interventions that involve the application of a treatment by a healthcare provider, the learning of mindfulness via MBSR substantiates participants’ proactive and participatory self-care. Similarly, we found positive change in participants’ attitude and behavior toward self-care; the vast majority reported being more aware of their need for care, acting on that need and being more able to communicate that need over the long term. This finding is similar to previous qualitative and quantitative studies that have found enhanced self-care among participants after an MBSR course.[9][11]
Parallel to this transformation in self-care, most participants reported a continuing long-term practice of mindfulness and for a large portion of the time they continue to be engaged mindfully in the activities of daily living. These findings generally complement those of other studies documenting ongoing mindfulness practice after MBSR training.[20][28][30][38]

Study 2: Health Care Provider Assessment of Patients’ Self-Care

The self-reporting of changes in attitudes and behaviors summarized in Table 2 indicates robust positive consequences for MBSR participants long-term. There has been no reporting in the literature of such changes observed by the clinicians who provide care for MBSR participants. We hypothesized that clinicians would observe these same changes. In combination with participant self-reporting, such clinician-reporting would further substantiate mindfulness as a vehicle for enhancing the proactive self-care at the heart of the model of participatory medicine.


Clinicians (n = 118) who were familiar to MBSR participants at the clinic described in Study 1 were sent a short, anonymous survey about the changes in self-care attitudes and behaviors of their patients after MBSR training. This included the clinicians who referred participants or were otherwise noted in the evaluations and applications as clinicians who might be interested in learning more about MBSR by 300 participants including those in Study 1 from 16 MBSR programs at the clinic during four and a half years from Fall 2007 through Winter 2012. The survey included the same 6 items on the MSCI used in Study 1; however, the items were revised to the third-person plural perspective: the clinician’s opinion of how much change had occurred for their patients “in general” as a consequence of MBSR. Also, clinicians were asked how many of their patients had taken MBSR.

Results and Discussion

A total of 31 clinicians out of the 118 who were mailed surveys responded by acknowledging that their patients had attended the MBSR program: nine primary care medical doctors, four psychiatrists or psychiatric mental health nurses, one specialist, six clinical psychologists, three physical therapists, seven clinical social workers or marriage and family therapists, and one naturopathic physician. Twenty clinicians responded that they did not recall which of their patients had taken MBSR and thus they could not complete the survey, and 67 did not respond to the survey. The 31 clinicians who completed the survey reported that they provide care to a combined total of 111 MBSR participants.

As shown in Table 7, health care providers acknowledged a robust positive change in their patients’ willingness and ability to take care of themselves indicating an enhanced participatory dimension of their health care. This is parallel to the results among participants demonstrated in Study 1. It is evident that in addition to the positive health status outcomes and increased personal willingness to care for themselves, these patients and their caregivers also showed a greater capacity for communicating and working together as a consequence of their participation in MBSR.

Table 7. Clinicians’ Assessment of Patients’ Positive Changes in Self-Care Attitudes and Behavior After MBSR Training

Overall Discussion and Conclusions

These studies have demonstrated in one community clinical setting that the learning of mindfulness meditation positively affects health in substantial and enduring ways. A number of dimensions of physical, mental, and social health were significantly improved over a two-month period and this improvement endured over a number of years. In general, those who participated in the MBSR courses continued the practices long-term. Participants’ attitudes toward self-care were transformed to the extent that they are taking better care of themselves and communicating their needs better to those around them. Clinicians noticed the same transformation in their patients who began the practice of mindfulness.

While acknowledging that the trajectory of mindfulness meditation does not point toward the outcome of curing disease, the results of these two studies parallel a growing library of more sophisticated and controlled studies showing that the practice of mindfulness can be an enduring path to relief of suffering. We rely on these to affirm the veracity of the findings we have presented and to help make the case for the role of mindfulness in the realm of medical care and therapy.

Despite these findings, this naturalistic study must be interpreted with caution due to a number of limitations. This research was conducted parallel and secondary to an ongoing clinical course and, as such, testing and self-reporting were woven into the matrix of the learning intervention with care to minimize distraction for participants. After 8 of 14 groups, we switched from administering the PSS-10 to the DUKE and this limited the sample size for each measure. Similarly, followup data were collected on a static date (Fall 2011) as opposed to a specific time point post-MBSR (e.g., one year) for each participant, and therefore the duration of time from post-MBSR to followup was variable. Additionally, without the benefit of a control group, we cannot make claims of causality regarding the impact of the MBSR intervention. Lastly, this was a study based on one clinic and one community with corresponding demographic limitations, so generalizations to other populations will be limited.

These studies have affirmed the value of a number of important contributions that the practice of mindfulness offers to the model of Participatory Medicine as described by Santorelli[39]: importance of body awareness, awareness of inner experience, a recognition of being “whole,” the liberation that comes with systematic mental training, self-regulation, and transformation. These studies build on this line of thinking and parallel recent research suggesting that mindfulness meditation transforms one’s intrapersonal relationship to enhance a greater capacity for proactive self-care.[40] Further research regarding self-care, mindfulness, and health care will enhance and fine-tune our ability to care for ourselves via this practice.

The intention of both Tom Ferguson and Jon Kabat-Zinn to plant the seeds for a version of medicine that is truly participatory is undeniable. Their respective approaches come from different directions but, at the heart, they both acknowledged the hunger we all have to be personally and proactively engaged during encounters with illness. Self-care, an engaged community of caregivers, attentive awareness, self-compassion, good communication, a transformation of attitudes and behaviors, and good information are all necessary ingredients for a successful model of Participatory Medicine.


The authors would like to thank Dr. Paul Salmon and Marie Pielage, PT for their thoughtful comments and suggestions during the development of the study, and Chelsey Ritner, BS for her assistance with preparation of the manuscript.


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